For extreme error cases, however, mean tree length starts out much too high in the inferred trees, becomes correct around the point where declared error is equal to true error, and then becomes much too low with further correction.
This failure has no effect on the conversion process and it is reported by the validator's maintainers that the failure may refer to a true error, a waning or a notice.
Our analysis presented above rests on the assumption that the used transcriptional regulatory network corresponds to the true (error free) TRN of yeast.
Because of the underestimate of the errors reported by LSQR, we checked the final locations by SVD to assess a true errors estimate (Waldhauser and Ellsworth, 2000).
However, it should be noted that the empirically-based standard errors which are used when making inferences about parameters with Wald statistics and asymptotic normality of estimators tend to underestimate the true errors unless the sample size is quite large [ 32] p. 467-468).
If set to 'True', the error array returned by get_error will be filtered, i.e. the array will be shorter in length than the unfiltered array (not padded with zeros).
As will be discussed, this variability was primarily due to animal-to-animal differences in ALA uptake and/or PpIX synthesis, local skin pO2 and relative photosensitivity of the skin, as opposed to true 'experimental error'.
At least for some downstream analyses, the benefits of eliminating true errors appear to outweigh the costs of obscuring a fraction of true genomic mutations.
However, to avoid underestimation of the true errors, the subjects were not aware of the future comparison between reported and measured values.
