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Cleavage of PARP effectively neutralizes its ability to participate in DNA repair and contributes to the commitment of a cell to undergo apoptosis.
The very existence of the data is remarkable; the data are testimony to the commitment of a clinical research group – to their patients and to the potential of science to promote knowledge that can benefit generations to come.
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Of course some of this is probably due to the commitment of an upfront $500 fee, but it's also because the process is just generally a lot less frustrating for customers.
Other SUMPs have remained on the shelf, ostensibly to show the commitment of a council to the sustainable mobility.
For consecutive seasons now, Karl Lagerfeld has used his Lagerfeld Gallery line to tell the world that he believes most women give over some part of their day to the commitments of a dominatrix.
"So to produce this report without the commitment of a single new unit of supportive housing is shocking".
The level and pattern of participation can give a clue to the commitment of participants in a virtual committee context.
Still, it's too bad the first Broadway revival of August Wilson's important play had to limit its scope to accommodate the commitments of a superstar's schedule.
It's kind of terrifying to realize that you have made the commitment of a lifetime, but it's a wonderful thing.
Since the maturation and activation of pro-caspases generally represents the commitment of a cell to the apoptotic fate, it is a highly regulated process (40, 41).
Hence, prior to the commitment of resources to such a trial in the development of a new treatment, the safety and clinical promise of the new treatment needs to be demonstrated with preliminary studies.
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