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In 1941 doctors at Carville began to test a derivative of the compound, called promin, on patients.
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It is generally believed that the Chinese tested a derivative design for the Pakistanis on May 26 , 1990
Genentech is testing a derivative of Avastin, rhuFab V2, in patients with macular degeneration, a leading cause of blindness.
The next step is to test the derivative in monkeys, and then people.
Therefore, we decided to test other derivatives that possessed a high activity and selectivity to the L. major enzyme over the human enzyme [ 15].
However, these techniques could be useful in the refinement and optimization stages of drug development, providing a simple, cheap and automatable way to test chemical derivatives for desired specificity profiles and activity in eukaryotic cells.
When hits are obtained in a drug discovery project, it is interesting to test similar derivatives in the hope that some will be more potent.
She expects to test the compound or a derivative among rheumatoid arthritis patients in a clinical trial, hopefully soon.
To test HDR efficiency using a derivative of the pDCC6 plasmid (Gokcezade et al. 2014) encoding cas9 and U6 2-gRNA-wg (hereafter called pDCC6-wg), both donor and pDCC6-wg were injected into embryos of an isogenized w stock (Bloomington Stock Centre ((BL)5905)).
To test whether the carbamate derivative had an improved permeability over its parent compound containing a primary amine, the absorption of ICEC-0782 was tested across caco-2 cells using the transwell assay.
To test this possibility, we expressed a derivative of wtLacI-tdRFP that can only dimerize and thus bind only one LacO site.
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