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Furthermore, it was able to significantly trigger apoptosis, to up-regulate p53, to block cells in the G2/M phase of the cell cycle and, finally, to slightly bind to DNA forming interstrand cross-links (ISCL).
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The rejection of Pedroni's no between-dimension null hypothesis indicates that the usage of either cheque payment, telegraphic transfer, card payment or electronic money, will significantly trigger the usage of another type of cashless payment.
Blocking studies revealed that α2 and β1 integrins significantly trigger the motile behaviour of the tumour cells.
Id1/3-PA7 could represent an exogenous anti-tumour agent that can significantly trigger cell-cycle arrest and apoptosis in ovarian cancer.
That TN-C itself represents that factor is an open question, since even the TN-C derived EGF repeat sequences do not significantly trigger EGFR autophosphorylation, although they do trigger EGFR-mediated activation of MAPK [ 34].
Hypercholesterolemia did not significantly trigger platelet changes in AD mouse models, supporting the hypothesis that the observed changes are AD-specific, while a cholesterol diet alone does not alter platelet serotonin levels, APP expression or the secretion of APPβ.
This is consistent with the result in Figure 3a, which shows that 15 μM NMDA failed to significantly activate ex-NMDAR and trigger Ca2+ influx.
We are the first to show that I3MO significantly triggers HO-1 induction and hereby inhibits migration in VSMC.
The most potent compound 10M selectively inhibited human hepatocellular carcinoma cells but not non-tumor liver cell proliferation in vitro, and significantly triggered SMMC-7721 cell apoptosis by cleavage of both PARP and caspase-3 in a concentration-dependent manner.
Anisotropic nanofibers significantly triggered the integrin β1 signaling pathway in NHDFs as evidenced by an increase of active integrin β1 (130 kD mature form) and phosphorylation of focal adhesion kinase (FAK) at Tyr-397.
As shown in Figure 4B, dexamethasone significantly triggered TrkB phosphorylation in our cortical neurons cultures.
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CEO of Professional Science Editing for Scientists @ prosciediting.com