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Gene-and-cell therapy offers solutions to severe problems faced by modern medicine, but several impediments obstruct the path of such treatments as they move from the laboratory toward the clinical setting.
The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems.
Such a wide error rate can leave patients vulnerable to severe problems, including seizures, unconsciousness and coma.
This can lead to severe problems, such as system frequency oscillations, and/or violations of power lines capability.
In 2001 doctors at GOSH used gene therapy to "cure" children who had a genetic condition that led to severe problems with their immune systems.
Yet children and the elderly are more vulnerable to severe problems from the flu, so for those populations it might be unethical to conduct trials using a placebo.
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Health problems were classified into two categories based on the severity of problem (0 = no problem, 1 = mild to severe problem).
The scale ranges from "no problem" (score 0) through "mild but clinically significant problem" (score 2) to "severe problem" (score 4).
Defects in imprinting in gametes can give rise to severe problem in embryogenesis and predispose affected individuals to associated diseases after birth.
In this study, haemoejaculate was perceived as a moderate to severe problem for around one quarter of sexually active men (table 2).
"Encroachment is a moderate-to-severe problem, and we're trying to catch it now so it doesn't become worse," Jefferds said.
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