Sentence examples for to rigorously explore from inspiring English sources

The REMD simulation was employed to rigorously explore the free-energy landscape of EGF unfolding.

Some forms of professional development may be too passive to adequately challenge participants to rigorously explore and reflect on new concepts (Penuel et al. 2007).

Our objective was to rigorously explore the morphology of ditrysian Lepidoptera and to analyze the extensively coded data to infer a hypothesis for the phylogenetic relationships within Ditrysia.

During analysis, we explored participants' attributes (e.g. gender, age), in which we had an a priori interest, against the various themes to rigorously explore emergent patterns in response by age and gender.

A key feature of the formal computational approach is the ability to rigorously explore, by in silico experimentation, the dynamic behaviour of the model to determine both the role of signal modifiers such as SOCS and the importance of parameter values.

It performs tree searches within a parsimony framework, using either exhaustive searches or, where exhaustive tree searches are not possible due to a large number of putative gene family members, heuristic searches are performed implementing the parsimony ratchet [ 86] with 200 re-weighting iterations for each of 20 ratchets; in order to rigorously explore tree space.

To more rigorously explore this possibility and to understand the mechanism of CCN5 in VSMC we employed RNA interference (RNAi) to knock down endogenous CCN5 expression in these cells.

We conducted a study using our gene cluster evolution simulator from [ 17], in order to (1) more rigorously explore the effects of the main tuning parameter (the 80% paralog coverage threshold for criterion selection) on CHAP's sensitivity and false discovery rate, and to (2) measure CHAP's runtime performance on gene clusters of varying complexity.

Here, we discuss three general evolutionary problems that have the potential to dramatically influence the evolution of cancerous traits, but remain to be rigorously explored empirically: the evolution of drug resistance and associated costs, cooperation and conflict between cancerous and noncancerous cells, and resource competition as a driver for the evolution of metastasis.

It might be expected that presence of multiple loci affecting WEC would reduce the selection pressure acting on each worm locus, although this is yet to be rigorously explored.

The low response rate clearly illustrates the challenge of eliciting the views of health professionals to inform implementation research; particularly where research uses questionnaires to try and systematically and rigorously explore factors influencing innovation adoption.