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Life is a very big thing, and to reduce the functionality of life to just one perception then you project it to the world.
To reduce the functionality of the RNA in the exosomes, we exposed the exosome fraction to UV-C radiation, as this treatment is known to have a damaging effect on nucleic acids [42] [44], [50].
Similarly, if one assumes that the main effect of missense errors is to reduce the functionality of the protein produced, then the cost of these errors is expected to depend greatly on specific details such as the structural and functional role of the amino acid at which the error occurs and the physiochemical differences between the correct and the erroneously incorporated amino acids.
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For genes with a pattern of sexually antagonistic fitness effects, nonsynonymous mutations that reduce the functionality of the protein might be beneficial to males but harmful to females.
It's not that retweets reduce the functionality of the trail of overlapping social circles, it's that they lock them behind the Wall.
While, arguably, HEX was first to market with their rubber sports band for the iPod Nano, they are now inexplicably creating more iPod watch bands for the millions of people out there who want to reduce the overall functionality of both their watch and their iPod in one fell swoop.
We hypothesize that binding of the anti-N-terminal antibody to ADM still allows receptor binding, but less efficiently, and thus reduces the functionality of ADM so that excess levels, which have been suggested to become harmful during the progression of sepsis, then get functionally neutralized to a certain limited extent.
It is likely that abnormal maturation of RBCs reduced the functionality of these cells and thus contributed to causing hypoxia.
Potentially, high BRE expression causes a misbalance in the BRCA1 multi-protein complex formation, thereby reducing the functionality of the complex and rendering cells more sensitive to radiation-induced DNA damage.
The dyes used in the photopolymerization process also reduced the functionality of the beta cells as insulin secretion decreased significantly with increasing dye concentration [44].
These combat- and trauma-induced skeletal muscle injuries are characterized by volumetric muscle loss (VML), which significantly reduces the functionality of the injured muscle.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com