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It has long been assumed that the action of cyclin D1, as an activator of cdk4 and cdk6 and leading to progression through the G1 phase of the cell cycle, underlies its pathological activity.
The BSB suggests laudable aims with which no-one should disagree: that the system will assist in eliminating discrimination… and that equality and diversity monitoring will also ensure that due regard is paid to progression through the levels by different groups… collected evidence will help regulators promote equality in the profession.
The activation of these genes leads to progression through the G1 phase of the cell cycle.
Each cluster contained functional groups of proteins involved in different nuclear processes related to progression through interphase.
Transcripts differentially regulated in both mutants are more likely related to progression through the L/Z transition.
The database includes data pertaining to progression through the screening process and data from the local population registers, the laboratories, and the company responsible for handling the mailings.
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This inflammation is assumed to contribute to disease progression through the production of inflammatory mediators.
IL-8 has been reported to contribute to cancer progression through potential motility-stimulating, mitogenic and angiogenic functions [ 29].
This was achieved by a phase-based physiological model to link progression through particular phases to the extent of gene expression (Fig. 8).
These results suggest that Plk4 haploinsufficiency may also lead to impaired progression through the cell cycle with the potential to lead to abnormal chromosomal alignment and segregation.
An interesting aspect of this finding is the ability of CLN1 and CLN2 to form a complex with CDC28 to promote progression through the cell cycle [12].
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CEO of Professional Science Editing for Scientists @ prosciediting.com