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All cases accrued in this study had local pelvic relapse and the median time to progression after primary treatment was 16 months (9 120) in the 13 cases that had complete response, whereas the time to progression for the persistent or progressive disease cases was 4 months (range 2 7 months).
The median time to progression for all patients was 3.7 months.
The median time to progression for the study group was 20.47 weeks (range, 8 46 weeks).
Time to progression for all 31 patients calculated from the start of second-line therapy was 3.40 months (95% CI, 2.73 4.07).
Figure 1 shows the time to progression for each patient.
with significantly improved time to progression for patients in the fulvestrant arm (Robertson et al, 2009).
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The oral multi-kinase inhibitor, Sorafenib, has shown significant efficacy in prolonging the Time-to-Progression for tumours in two large, Phase III trials and is the standard treatment for patients with advanced HCC [ 11, 12].
Median time to progression (TTP) for patients treated in first to fourth line was between 6.2 and 7.6 months.
Cox acknowledged that there were problems in getting young women to take up careers in science and engineering, and said there were "big problems" that needed to be addressed when it came to career progression for women.
Median time to PSA progression for the whole cohort was 94.5 months (range 3 169.6), while median time to death has not been reached yet.
The median time to disease progression for all 27 patients entered into this study was 18.1 weeks (range 1 to 76 weeks).
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