This may have been problematic because the tiling probes were not designed for explicit use with the barcode probes, which could lead to unanticipated cross-hybridization of barcode samples to tiling probe features.
Intensities of target hybridization to respective probe features were detected by laser scan of the array.
All complexes were utilized as pre-catalysts in a comparative study to probe relevant features of the palladium active species during high temperature Suzuki Miyaura cross-coupling catalysis.
Second, molecular dynamics simulations with solvent can subsequently be employed to probe conformational features in the presence of polymerase enzyme responsible for DNA replication, using structures computed in the energy minimization searches as initial coordinates.
Electrochemical impedance spectroscopy is helpful to probe the features of surface-modified electrodes.
Comparing different radiotracer investigations may often be desirable in order to probe different features of the tissue being targeted.
We have exploited the relationship between solvent exposure and intrinsic fluorescence of a single tyrosine residue, Tyr10, in the Aβ sequence to probe structural features of the monomeric, oligomeric and fibrillar forms of the 42-residue Aβ1-42.
We have demonstrated the use of the DW for SOCT, in combination with Fourier domain LCI (fLCI) and light scattering spectroscopy (LSS), to probe morphological features in tissue phantoms [ 8], and for obtaining cell nuclear size to diagnose malignant states in ex-vivo tissue samples [ 12].
Further constraints on probe features, GC% and the lower-bound of Tm, are available in the output browsing interface.
However, using α values between 10-6 and 10-7 resulted in a high percentage of known SFPs within probe features being excluded.
After mapping our Affymetrix probe features to genes, we created a dataset where the level of each gene was represented as the expression level of the probe (for that gene) with the highest average expression across samples (see methods).
