Where financial constraints prevent comprehensive adoption of less-toxic agents, a risk factor-guided approach to choosing an initial regimen may reduce the incidence of lactic acidosis.
Lack of available data and low adequacy of experimental protocols prevent comprehensive risk assessment.
Despite a range of potential human health impacts that could ensue, there are significant data gaps that prevent comprehensive assessments of human health risks associated with animal feed.
In addition, we evaluate evidence that current feeding practices may be associated with adverse human health impacts, and address the data gaps that prevent comprehensive assessments of human health risks associated with animal feed.
To date, logistical obstacles have prevented comprehensive tracking of timber transport distances and emissions.
An obstacle of America's own making has long prevented comprehensive negotiations over weapons of mass destruction in the Middle East.
He also cited other geographic "holes," one around the Somali capital, Mogadishu, and another in eastern Angola, where conflicts had prevented comprehensive inoculation programs.
Messy problems involve divergent, at times conflicting, interests and perspectives and their urgency prevents comprehensive analysis.
The notion that urgency prevents comprehensive analysis is demonstrated in the West's dilemma over engagement in Syria.
In contrast, deletion of Trim28 in ESCs results in a rapid loss of pluripotency and growth arrest, preventing comprehensive analysis of DNA-demethylation dynamics in these cells.
