The smaller RNA types are too small or too tissue-specific to have their XCI status determined in these studies; furthermore, high homology to another gene might prevent assessment of XCI status and the X is enriched for large inverted repeats [ 40].
Therefore, at present, these limitations prevent assessment with confidence of differences in genetic load between women and men with SLE.
But this approach would potentially result in a different number and combination of genes for each outer split, and would thus prevent assessment of a given combination of genes in predicting breast cancer mortality and recurrence.
This design also limited our analysis to correlations, preventing assessment of causality or changes over time.
However, to prevent any assessment bias, different physiotherapists with no access to the subjects' data were specifically assigned to perform either assessment or training.
Several participants highlight the suggestion that importance of continuous training is important to prevent risk assessment becoming 'a tick box exercise' and for clinicians to understand the significance of the procedure to ensure follow-on action.
Internal validation is useful to prevent optimistic assessments, but it does not inform about the performance of the model in other samples of the same population [ 60].
However, cerumen impaction is the preferred term since it is consistently used in clinical practice and in the published literature to describe symptomatic cerumen or cerumen that prevents assessment of the ear.
The relatively small number of confirmed deep infections prevented assessment of differential ability of this method to identify different types of surgical site infections.
Our low mortality rate prevented assessment of the STSS scores' discriminatory potential with regard to H1N1.
