Deciphering the knowledge of HIV protease specificity and developing computational tools for detecting its cleavage sites in protein polypeptide chain are very desirable for designing efficient and specific chemical inhibitors to prevent acquired immunodeficiency syndrome.
We therefore recommend that directly observed therapy for diagnosed TB cases with drug-sensitive disease be strengthened to prevent acquired drug resistance and a country-wide drug resistance survey be carried out to establish the national burden.
Recently, targeting both Src and ER has been shown to prevent acquired resistance to tamoxifen therapy [ 38].
Medical consultation for patients with ongoing symptoms is provided by the state TB clinicians in an effort to identify slow response earlier and to prevent acquired drug resistance.
These synergistic treatments could not only alleviate primary resistance to sorafenib but also prevent acquired resistance.
The two clinical challenges where we seem likely to benefit most directly from adopting the perspective of somatic evolution are predicting progression to malignancy and preventing acquired therapeutic resistance.
We examine two key clinical challenges as opportunities for the integration of evolutionary biology into cancer biology: predicting progression to malignancy and preventing acquired therapeutic resistance.
Israel has threatened military strikes against Iran's nuclear facilities to prevent it acquiring a nuclear weapons capability.
