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In the present study we utilized three widely used prostate carcinoma cell lines, namely, PC3 and DU145 castration-resistant cells, and LNCaP androgen-dependent cells, and utilized transgenic and immunological strategy to pinpoint the function of Mitostatin in these cells.
To pinpoint the function of each stem-loop beyond base pairing, we examined their contributions to stability and Hfq interaction.
However, to date, it has been difficult to pinpoint the function of RNA granules and other bodies (Decker and Parker, 2012; O'Connell et al., 2012).
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It is however of value to pinpoint the role of NE within the LC.
However, it is essential to use adequate evaluation methods and techniques which give reliable quantitative and qualitative variables in order to pinpoint the functional state of the sensory, central, and motor components of the postural function.
Though further investigation will be required to pinpoint the exact function of Rv3802, examination of the mycolic acid synthetic pathway suggests a role as a Pks associated thioesterase or as a mycolyltransferase.
This new tool would allow us to pinpoint the exact function of Rn protein and provide a handle for uncovering the molecular mechanism of ORN diversification.
A better understanding of the role of Mnn4p is expected to help to pinpoint the molecular functions of FKTN and FKRP with respect to the post-phosphoryl modification on α-dystroglycan.
Knowledge of the proximodistal expression pattern may therefore indirectly facilitate pinpointing the function of Adhesion GPCR orphans.
Mechanistic studies of the genes identified in the present study, though beyond the scope of the present report, are ongoing by our combined laboratories that aim to pinpoint the precise functions and mechanisms of the identified transcripts for lens epithelial cell mitochondrial regulation, lens cell survival, lens cell differentiation, lens development and the maintenance of lens transparency.
It may therefore be difficult to pinpoint the cell-of-origin for retinoblastoma.
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