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One hypothesis is that the evolutionary history of the real CRMs is more complicated than our simple simulations assume, for example, they have been "exapted" (de Souza et al. 2013) from other functional sequences to perform a different function.
Each FPGA contained a large number of these programmable logic blocks and through appropriate SRAM programming cells, every logic block in the device could be configured to perform a different function.
Notably the substitutions are quite divergent (R -> P/E, H->Q and N ->F/Y), raising the doubt whether the tsetse proteins display endonuclease activity or whether this protein family has evolved to perform a different function.
Similar(56)
This proposal that the concept of knowledge may have changed over time so that what we now call 'knowledge' may sometimes perform a different function to the one that our original concept of knowledge was supposed to track is clearly of central importance to debates about the value of knowledge, as Craig's account of objectification indicates.
But it can perform a different function.
In Kenya, where I live, the multiplying slums in which much of the urban population live perform a different function.
In a strictly mammalian pathogen, such as M. tuberculosis, it is likely that these proteins perform a different function.
That does not include 2005 sales figures for the cosmetic use of Botox, a toxin injected into the skin, which performs a different function: relaxing the muscles underneath wrinkles.
Several visors are available, and each performs a different function.
There are several different types of innate lymphoid cells, with each type performing a different function.
It is possible that Nanog performs a different function in lower vertebrates, which is co-opted during induction of pluripotency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com