Sentence examples for to optimize the potency of from inspiring English sources

To optimize the potency of the ECT, a balance between adequate anesthesia and optimal duration of induced seizure is crucial.

Topliss operational method was used to optimize the potency of molecules.

Further synthetic modification was undertaken to optimize the potency of amide compounds.

Information from X-ray crystal structures were used to optimize the potency of a HTS hit in a Hsp90 competitive binding assay.

In our desire to optimize the potency of 5, compounds 6 (3ξ-fluoro) and 9 (3β-sulfamate) designed to increase the stability and oral bioavailability of 5, respectively were evaluated in vivo.

Over the years, research has focused on strategies to optimize the potency of topical steroids while minimizing adverse effects.

These approaches include both synthetic methods for discovering small molecules capable of acting like genetic mutations, and techniques that combine the advantages of genetics and chemistry to optimize the potency and specificity of small-molecule inhibitors.

Here, we applied multiple approaches to optimize the potency and selectivity of our reported alloxazine scaffold.

Antiviral evaluation in a virus-cell-based assay for DENV proved this approach to be successful, after which another twenty-four molecules were produced to further explore and optimize the potency of this novel class of hybrid inhibitors.

The present study was directed at optimizing the potency of SIRT2 inhibitors containing the neuroprotective sulfobenzoic acid scaffold and improving their pharmacology.

We firstly design and optimize the potency of adjuvant combinations of emulsion-based delivery systems, using EV71 candidate vaccine as a model.