Sentence examples for to optimize efficacy from inspiring English sources

Given the increasing prevalence of VAP caused by MDR Gram-negative bacteria, it is imperative that optimal antimicrobial treatment strategies be employed to optimize efficacy while minimizing the emergence of further antibiotic resistance [ 33].

The findings provide novel insight into a target for NAC, beyond the generic characterization as an antioxidant, resulting in neuroprotection and offer a feasible combinatorial strategy to optimize efficacy and safety in dosing of NAC for treatment of neurological disorders involving ferroptosis such as ICH.

The antigens recognized by T cells, the techniques to procure and grow tumor reactive T cells, the conditioning of the recipient to optimize efficacy, and the results of clinical protocols are reviewed herein.

This review highlights current research in using biological transporters as a proactive approach in drug delivery to optimize efficacy in the early stages of drug development, and as a target for rational design of prodrugs as novel therapeutic agents.

Future studies may combine reduced-dose fibrinolytic therapy with GP IIb/IIIa inhibition to optimize efficacy and safety.

The dose of lurasidone could be adjusted at any time, based on the clinical judgment of the Investigator, to optimize efficacy and tolerability.

There have been many attempts to integrate pharmacokinetic and pharmacodynamic data to provide dosage schedules which optimize efficacy and minimize opportunities for the development of antimicrobial resistance in both laboratory animal studies and human clinical trials.

Pharmacokinetic/pharmacodynamic research models offer promising approaches to define the determinants of resistance selection and drug doses that optimize efficacy and reduce resistance selection.

A secondary aim is to investigate the association between baseline measures and outcome, which might improve treatment selection and thus optimize efficacy and cost-effectiveness.

However, these veterans underutilize smoking cessation treatment, which suggests that interventions for rural veterans should optimize efficacy and reach.

In the present study, we evaluated protection efficacy and immune responses in layer chickens, which had been immunized with a double immunization in order to optimize the efficacy of the vaccine.