We then examined the data across sites for behaviors that observers consistently (>= 50% of the time) identified as "unable to evaluate" or "did not observe" in order to evaluate the utility of the evaluation tools.
Sediments were exposed to CO2 and hydro-geochemical effects were observed in order to improve general understanding of trace metal mobility, quantify carbonate influence, assess risks attributable to fresh water resources from a potential leak and aid monitoring measurement and verification (MMV) program design.
The rabbits are then observed in order to determine whether or not irritation occurs over the next three days.
At least two consecutive tumour measurements had to be observed in order to retain CR and PR.
An initial 14 patients were accrued, with at least one response or alternatively three SD needing to be observed in order to proceed to the second accrual stage with an additional 11 patients.
Nested RT-PCR is also more time consuming and stringent procedures need to be observed in order to minimise the risk of false positives due to PCR product cross contamination.
During all hospital treatment and at 28-day, the vital status will be observed in order to be able to estimate the global mortality and for subgroups in the study population.
In addition, at final follow-up a significant recollapse of the longitudinal foot arch for both the medial column and, to a greater extent, the lateral column had to be observed in order to minimize the number of patients with persistent correction to 62%% medially and 35%% laterally.
While the topical application of hormones is certainly a suitable alternative to a systemic HRT, it must be ensured that such a treatment is also administered by a dermatologist experienced in endocrinology given that concentrations and application areas need to be observed in order to avoid systemic side effects.
The 395 day period for pre- and post-index observation was selected as the maximum period of time that would need to be observed in order to measure chronic medication use, since prescription refills cannot extend beyond 1 year and this 395 day period allows for 1 year plus a 30 day grace period for prescription renewals [ 16].
The longer survival of transplanted FAP patients is by itself a risk factor for eye disease development and, therefore, all FAP patients, transplanted or not, require a life-long ophthalmologic follow-up with adjusted intervals to the different manifestations observed, in order to maintain an optimal visual function and a good quality of life provided by the liver transplantation.
