The possible mechanism due to MSC's immunomodulatory property through activation of mTORC2-Akt and inhibition of mTORC1-p70S6K signal pathways which may lead to modulate the expression of inflammation cytokines.
NRG2, another important nitrate regulatory gene, has been reported to modulate the expression of NRT1.1 in both presence and absence of NH4+, indicating that NRG2 can affect both nitrate transport and signaling functions of NRT1.144.
In addition, some genes appear to be differentially modulated by nicotinic acid and MgSO4, both known to modulate the expression of BvgA/S-regulated genes.
We review how chromatin regulation acts locally to modulate the expression of specific genes and more broadly to coordinate gene expression programs during transitions between cellular states.
The ability to modulate the expression of many genes placed the transcription factors as promising biotechnological targets to develop stress tolerant cultivars.
Their pharmacological behavior against PLA2 enzymes as well as to modulate the expression of inducible cyclooxygenase 2 (COX-2) and mPGES-1 enzymes is also described.
Specifically, cyclin D1b was found to modulate the expression of a large transcriptional network that cooperates with androgen receptor (AR) signaling to enhance tumor cell growth and invasive potential.
Previously, we characterized the transcription profiles of ten Rbohs in Arabidopsis under hypoxic stress and found Rboh D is involved in primary hypoxia signaling to modulate the expression of hypoxia-inducible genes under hypoxic stress (Yang and Hong 2015).
H2O2participates in hypoxia signal transduction to modulate the expression of a set of genes encoding heat-shock proteins and other groups of ROS-mediated proteins (Pucciariello et al. 2012b).
This functional architecture allows the Tup1-Ssn6 to modulate the expression of genes required for the response to a variety of cellular stresses.
Interest in modifier genes keeps growing because of their ability to modulate the expression of monogenic or multigenic traits and diseases [1], [2].
