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If the multiple loci mechanism pertains, then the convergence of several distinct loci would have been necessary to produce regional significance, and thus, each implicated locus will be of relatively low-frequency in the sampled families and more likely of moderate to larger effect.
Especially the latter seem to produce more highly powered studies due to larger effect sizes of individual genetic variants [ 121, 126].
Test-retest reliability from Time 1 to Time 2 demonstrated mainly moderate to larger effect sizes for patient self-report and parent proxy-report (Table 2).
The results showed a bias to larger effect sizes of the risk alleles in the Southern Europeans relative to the Central Europeans.
In a behavioral intervention trial, the intervention effect estimate is influenced by study sample composition; excluding those with severe problems can lead to larger effect estimates because inference is restricted to a more healthy reference population (Humphreys 2000).
Our findings showed a bias to larger effect sizes of SLE loci in the Southern Europeans relative to the Central Europeans together with clines of SLE risk allele frequencies.
Similar(52)
Moreover, at comparable doses, internal irradiations led to larger effects for the three bioassays.
Most of these measured changes can be interpreted as clinically relevant outcomes with medium-to-large effect sizes.
These improvements were statistically significant with moderate-to-large effect sizes.
Thus, the comparison of the map and comprehension tasks created a medium-to-large effect for looks at the car.
Three of six significantly different depression symptoms were of moderate-to-large effect size, with the older group having a lower proportion reporting the symptom.
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