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The key criteria proposed to judge the utility of a new end-point primarily relate to its ability to accurately and reproducibly predict the eventual phase III end-point for treatment effect, which is usually assessed by a difference between two arms on progression free or overall survival, both at the patient and more importantly at the trial level.
Insufficient data exist to judge the utility of RYGB to treat diabetes in patients with BMI <30 kg/m.
We believe sustained LC is another measure that should be used to judge the utility of more intensive therapies such as this.
To judge the utility of initial insulin therapy, consider what is required from both patients and providers when either insulin or OAD is started (Table 1).
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Furthermore, we examined an additional clinically important outcome, namely adverse events resulting in discontinuation of antifungal prophylaxis, which provides more information to judge the overall utility of mould-active prophylaxis.
The surgeons also judged the utility of objective measurements (e.g., intraoperative biomechanical tests).
In judging the utility of any health screening program, a central question is whether the condition is sufficiently common and sufficiently serious to justify the costs of screening.
The respondents also judged the utility of incorporating objective measurements (e.g., intraoperative biomechanical tests): 13.3% (n = 14) responded that such measurements would be "very useful" and 61.9% (n = 65) responded that they would be "somewhat useful".
As a general rule, it is crucial to judge the effectiveness and utility of a specific SMS intervention by observing changes to both proximal and distal targets, and not to rely solely on changes to a distal outcome that can be influenced by multiple factors, such as A1C.
One account stresses that the two domains are oriented around utility-maximization. Utility criteria deployed to judge the worth of architectural objects are exemplary subjects of democratic debate, policy analysis, or community consensus.
Mozi, as we noted above, appealed to what he regarded as a natural utility standard to judge the acceptability of yánlanguage use and Confucius relied more on past usage ranging back to the mythical sage kings.
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