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Famously, Heseltine is one of the few senior ministers in recent times to have both understood organisations and tried to introduce substantial reform of Whitehall.
Job creation will be a top priority in the second Obama administration, and there is an opportunity to introduce substantial reforms that will produce the next decade of job creation.
"This year, we remain on course to introduce substantial changes in our service -– including tripled to quadrupled Internet speeds, a new more modern TV interface, doubling of our On Demand library and an even more reliable network –- all of which we believe customers will cheer over".
The computational gene prediction methods produce protein sequence sets that represent the theoretical proteome of Toxoplasma gondii; however, the datasets of predicted protein sequences are quite different and are likely to introduce substantial inaccuracy [10] [12].
Positional errors in street geocoding were found to introduce substantial bias and error in the analysis of the effects of traffic-related air pollution on children.
While direct information about socioeconomic, education, or insurance status was not available, the use of area-level measures as a proxy for individual SES is a standard approach 17, 27 and unlikely to introduce substantial bias.
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We found that plausibly high levels of background immunity (perhaps due to cross-reactivity) and plausibly low levels of boosting following infection could introduce substantial biases to the estimates of cumulative incidence.
These changes likely introduce substantial noise to comparisons of physiology and life-history parameters with rate of evolution.
These sensitivity analyses show that alternative definitions of cut-off levels and conversion units do not introduce substantial changes to the results.
NSAIDs as well as steroids were not included in our case definition to have little specificity to be a treatment for gout and would, therefore, introduce substantial gout misclassification [ 1].
As the SPKF/UKF does not introduce substantial computational burden, when compared to EKF, it is argued that SPKF/UKF algorithm may become a strong candidate for on-board implementation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com