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These culture-based methods can be used to interrogate with high efficiency the immune repertoires in order to characterize the frequency, function and specificity of naïve or memory T cells and to isolate potent and broadly neutralizing monoclonal antibodies.
This bias leads to areas of the genome that are difficult to interrogate with HTS which may require higher coverage, multiple HTS applications or necessitates improvements in HTS technology to be able to be sequenced to a sufficient depth to detect variants.
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Nucleotide and peptide sequences of ISAC, IRAC I and AM407396 were used to interrogate databases with the same results.
KvarQ was designed to interrogate positions with known mutations.
The risk machine approach, therefore, is an efficient and practical way to interrogate data with binary outcomes, free of the usual hazard of model misspecification.
Kondo's cleaning method encourages people to interrogate their relationships with their things, with the hope of transforming those relationships for the better and making people think twice before bringing a new item home.
He also explained that the torture technique known as waterboarding was particularly useful with people like Khalid Sheikh Mohammed, because being able to "interrogate him effectively with these techniques was vital in giving us the knowledge we needed in order to defeat al-Qaida".
TopHat [48] was executed with the following command-line options: -g 5 --solexa1.3-quals -p 8, and examined with the Integrative Genomics viewer (IGV) [49] to interrogate predictions made with the Shannon pipeline.
With such technological advances, it is now feasible to interrogate phenotypes associated with the loss-of-function of many genes in mammalian cell culture systems.
Technically, it refers to datasets that are too large and complex to manipulate or interrogate with standard methods or tools.
Here, under the influence of the fashionable teachings of Ëcole Philippe Gaulier (and of an accidental ecstasy pill), Dave begins to interrogate his relationship with his clown – a cranky thirtysomething lesbian comedian called Zoë.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com