Sentence examples for to inhibit with from inspiring English sources

Further studies of NMR and molecular dynamics have showed the capacity of these hybrid molecules to change their bioactive conformation depending on the binding site, being capable to inhibit with different shapes BuChE and residually AChE.

In unperturbed cells, the Aurora phenotype predominated suggesting that Aurora B is a relatively 'easy' kinase to inhibit with the cellular EC50 approximating that of the 120 hour GI50.

The NS3 helicase is a remarkably difficult protein to inhibit with small molecules.

This was thought to be a result of peri-implant resorption, which we hoped to inhibit with the coating.

In gupigs with sub-acute bronchitis caused by SO2 gas exposure, coughing is difficult to inhibit with centrally acting antitussives such as codeine.

This rapid turnover mechanism is likely difficult to inhibit with exogenous ligands in a clinically significant manner, but this prediction requires further study.

A total of 5 × 10 DT40 cellss cells were treated for 6 h with 10 μM 1NMPP1 (to inhibit CDK1) with or without 100 nM BI2536 (Plk1 inhibitor).

Out of these two compounds were found to inhibit PTP1B with significant inhibitory activity in in-vitro inhibition assay.

Imatinib effectively inhibits KIT with the juxtamembrane-type mutation, but fails to inhibit KIT with certain activation loop (exon 17) mutations, such as D816V in mastocytosis (Ma et al, 2002; Heinrich et al, 2003a, 2003b, 2006a).

Several β-mannanases from Streptomyces strains (Kumagai et al. 2013) and Cellulosimicrobium sp. (Kim et al. 2011) had a similar tendency to inhibit activity with Zn2+ ion.

Serendipitously, Ches was found bound to NanB at the enzyme active site, and was found to inhibit NanB with a Ki of ∼ 0.5 mM.