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Administration of the D2 agonist quinpirole (10 μM; n=3) failed to induce substantial changes in EPSP amplitude (8.5±1.3 mV compared to 6.4±1.2 mV) (Table 1).
These three groups failed to induce substantial new bone formation and resulted in the ingrowth of cells with fibroblast-like morphology into the defect zone.
Over a thirty-day recovery period, the implanted Sema3A gradient was sufficient to induce substantial migration of neural progenitor cells to the hydrogel and to promote differentiation of these cells for neuroregeneration at the injury site.
These results reveal that contact activation and platelet adhesion have a strong synergistic effect on coagulation on blood-contacting materials even though these events in isolation are not sufficient to induce substantial thrombin formation.
These studies demonstrate that substrates can be expected to induce substantial modifications in the electronic structures and band topologies, adding to the challenge of synthesizing films which support nontrivial topological states, especially films with band gaps large enough for room temperature applications.
The process parameters were deliberately set to induce substantial particle agglomeration.
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Ablation of FcγR binding by IgG4 is a critical factor, since in vivo studies have been demonstrated that IgG4 monoclonal antibodies can bind to FcγRIIIA and induce substantial lymphocyte depletion in patients [ 56].
In experimental settings, a Vt of 10 to 15 ml/kg results in pressures of around 10 to 20 cmH2O and can induce substantial damage in a short time [ 21].
In Sweden, the goal to replace fossil fuels could induce substantial changes in the current management and use of forests.
These artifacts induce substantial SUVmax overestimation compared to the reference SUV for PSF algorithms at SBR1 and SBR2 leading to substantial MTV underestimation in threshold-based segmentation.
However, recent studies have found that silica nanoparticles induce substantial lung inflammation and are cytotoxic to various cell types [7, 8].
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