Sentence examples for to induce efficacious from inspiring English sources
First, the subunit vaccine approach attempting to induce efficacious immunity by unique antigens in defined adjuvants.
In the case of immunogenic tumours, single-agent CTLA4 blockade was enough to induce tumour shrinkage, whereas in other models anti-CTLA4 synergised with other treatment modalities to induce efficacious antitumour immune responses (reviewed in [35]).
In addition, since a number of responses were due to cross-reactivity between rare and frequent peptides, we surmised that a number of these very rare peptides, which are unlikely to have been found in the viruses from our infected subjects, may not induce efficacious anti-viral responses, but rather represent decoy responses.
TAS2R agonists induce efficacious bronchodilation in murine models10,11,12 and human ASM cells/tissues.
Thus, there is a clear need for the design and development of systems to overcome these hurdles and allow for the translation of safe and efficacious treatments to induce angiogenesis.
First, mycophenolate mofetil (MMF) was shown to be at least as efficacious as oral/intravenous CY to induce a good renal response at 6 months in several pivotal randomised studies.
Mucosal, as opposed to systemic vaccination is often more efficacious against mucosal pathogens due to their ability to induce secretory IgA [1], [2].
Thus, it is conceivable that the combination of HD IL-2, to induce T-cell expansion, and PD-1 blockade, to eliminate tumor-induced immune suppression, might prove equally or more efficacious in select patients.
Therefore, MMX mesalazine appears to be efficacious as maintenance therapy regardless of the 5-ASA formulation used to induce remission.
By reducing AAV's tendency to induce adverse reactions that hamper gene therapy, Chan hopes to one day bring long-lasting and more efficacious gene therapies to medical treatment centers worldwide.
