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It is unknown at the moment whether increased STIP1 levels stabilize a complex containing Hsp90, preferentially leading to increased turnover of Hsp70.
Bafilomycin A1 increased the accumulation of starvation-induced LC3II that remained inhibited by H2O2, meaning a loss in PE conjugation was responsible, as opposed to increased turnover of LC3II.
Landowners and conservation stakeholders who relied on partner farmers to manage such sites often struggled to recruit and retain their participation, leading to increased turnover among managing farmers and to some sites being under-managed.
The decreased levels of in EGFR in HDAC6-knockdown cells, which correlated with increased acetylation of microtubules, were due to increased turnover of EGFR protein.
In both EPO transfected groups, the spleens were enlarged due to increased turnover of erythrocytes (Fig. 1G).
We propose that this alteration in the level of secreted factors in the microenvironment directly contributed to the increased tendency of Id1−/− LSK cells to enter the cell cycle, leading to increased turnover and premature exhaustion of HSPCs.
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Biologically, our data from experiments in tadalafil treatment supports that histological changes are due to the increased turnover of muscle degeneration and regeneration.
Damage to communities from increased turnover in social housing and less affordable, larger homes remaining empty.
Upregulation of Dtna in the mdx mouse might indicate an attempt to compensate for the increased turnover of the protein, in order to stabilize the post-synaptic side of neuromuscular junctions of affected muscle fibres, and retain neuronal connection.
High fecal calprotectin (f-calprotectin) levels were shown to correlate with an increased turnover of leukocytes in the intestinal barrier and granulocyte migration towards intestinal lumen [7], [8].
To study whether the increased turnover of naive CD8+ T cells concurred with other alterations within this subset, we analyzed the naive T-cell pools of the elderly subjects in more detail.
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