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The Luminex platform is capable of measuring the expression of 100 specific antibodies per well, resulting in decreased signal artifacts per well, in addition to increased specificity since two specific capture antibodies per molecules are required to bind before quantification takes place.
As shown previously, the increase in possible combinations of heterotetramers leads to increased specificity in enzyme kinetics.
The methods adopted by fusion detection tools to shrink the list of candidates lead to increased specificity but reduced sensitivity.
Theoretically, the use of recombinant antigens should lead to increased specificity and, possibly, increased sensitivity as well.
SPIDER greatly reduced the initial number of articles identified on a given search due to increased specificity, however because of lower sensitivity omitted many relevant papers.
Here target sites that appear not to be conserved between multiple species are filtered out from the search results, removing false positives, and leading to increased specificity.
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Additional PCR on obtained products was conducted with either RATZEB1 or RATZEB2 satellite specific primer, and inner adapter-specific primer to increase specificity of amplification.
To increase specificity, a differential immunoblotting technique involving 2 specific antibodies, directed against the amino- and carboxy-termini of PrP, has been developed (10, 28 ).
Long-range PCR (L-PCR) amplifications were performed first with primers specific for the target DNA regions to increase specificity [GenBank accession no. NG_000004.2 (National Center for Biotechnology Information 2009)].
To increase specificity, all serum samples that indicated probable infections were further investigated with more specific ELISA techniques.
He ascribes this to increasing specificity and difficulty in the type of questions being asked as people get used to the service, leading to harder answers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com