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We have now expanded Figure 2 to include further experiments and analysis of the nature of bidirectional RNP motion (see below).
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We plan to include further matched aCGH/expression experiments as and when they become publicly available.
We note that the model described below can be expanded or modified to include further interactions as new results from experiment and observation dictate.
Future work may include further RAM experiments, and more efficient methods to extract information over an extended period of time instead of one controlled browsing session.
We further reduced the collection to include eight experiments with sample size larger than 5, based on the shape of the distribution of correlation coefficients obtained from simulations (Supplementary Fig. S6).
Since neuropeptides have great potential in treating various CNS disorders, including pain, further experiments are ongoing to establish the potential of these new SAN nanoassemblies for drug delivery across the blood brain barrier.
Twenty candidate reference genes were included for further experiments and statistical analyses (Table 1).
Data for PC5S (P = 0.056) which was included in further experiments (see text) is also presented.
Additionally, we used LNCaP cells but these did not survive in hypoxia and therefore were not included in further experiments.
Furthermore, DMPC hindered accurate absorption detection because of its high background absorption, and thus, it was not included in further experiments (data not shown).
It remains to be further experiments to test the idea.
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