This is consistent with the idea that, in an uncertain feeding environment, the variability serves to implement a trial-and-error diversification of the feeding movements until a movement succeeds [21], [58].
Our aim was to implement a care trial for patients with acute ischemic stroke.
In terms of clinical trials, the mutually exclusive nature of the RTK/RAS alterations also renders it technically feasible to implement a multibiomarker-based trial, 63 in which multiple targeted compounds are tested in different biomarker-defined populations within a single trial design, as has been recently described for non-small-cell lung cancer (BATTLE trial).
This paper describes the two-phase study, including training and development of the research infrastructure in the Ecuadorian university necessary to implement a randomized controlled trial.
This study adopts a multiple-baseline method to implement a methodologically rigorous trial of an innovative intervention in which radiation therapists take an active role in providing sensory and procedural information and anxiety reduction techniques using a consultation prior to treatment planning and treatment at key time points during the patient's radiotherapy journey.
This article provides an understanding of the groundwork required to set up and implement a trial of a complex intervention within the pre-hospital setting.
In addition to supporting the National Institutes of Health randomized controlled trials of Ebola treatment (27 ) and vaccines (28 ), CDC staff worked with Sierra Leone authorities to implement a parallel Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE), an adaptive, phased-introduction trial of a vaccine candidate among health workers in that country (8, 9 ).
Fourth, Gunpo is neither too large nor too small to implement a community-based intervention trial with a limited budget.
There are five sites currently implementing preventive HVT protocols, however, a massive scale up of site capacity is expected as South Africa prepares to implement a phase III licensure trial in the country in approximately 2015.
The Look AHEAD Trial is one of the longest prospective randomized clinical trials to implement a lifestyle intervention targeting weight loss and improvement in fitness in overweight and obese adults with T2DM.
For any trial to implement a stopping rule successfully there must also be prompt feedback and processing of response and survival data ready for up-to-date analysis.
