Interestingly, the wood clade fungi carry one Slp1 homolog that lacks a predictable signal peptide, suggesting that this protein may have a divergent function than other secreted Slp1 homologs.
c-Raf and MAP3K8 are two serine/threonine kinases which are associated with cellular transformation, but which are suggested to have divergent functions in cellular physiology despite their high sequence homology.
Clusterin (CLU), also more expressed in tumours from survivors in our previous studies, seems to have divergent functions in cells.
Although the mechanism by which HDAC are involved in rice development regulation is unclear, those rice genes seem to have divergent developmental functions compared to closely related homologues in Arabidopsis.
Interestingly, CXCR7 and CXCR4 appear to have divergent cellular functions with CXCR7 influencing cellular adhesion and CXCR4 directing migration, suggesting differential chemokine signaling mechanisms [36], [37].
Eighteen studies that had a divergent design.
Whether the duplicated NAC genes correspond to genetic redundancy or have evolved divergent functions remains to be further functionally characterized.
There are likely important behavioral differences between these populations, but the ten genes contained within this GO term, appear to be genes that have many divergent functions and the behavioural annotations are mostly related to mice.
Closely related homologs were hypothesized to have either redundant or divergent functions according to phylogenic studies [ 40- 42].
Whether the duplicated CAD genes correspond to genetic redundancy or have evolved divergent functions, they must be involved in important processes in the plant to be retained in these two very different eudicot species.
