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To further explore the basis in the slope difference, we have performed complementary experiments using antibody PHE03S, raised against uranyl-DCP but, presenting a strong cross-reactivity toward the DCP chelator.
To further explore the basis of the discrepancy in the level of asymmetry of divergent expression recovered by our results using the XB+XL probemask and previous studies, we re-analyzed testis expression data from XL, XB, and HXLXB using the XB/XL gDNA probemask that was based on our new gDNA hybridizations.
In order to further explore the basis of this post-activation-specific silencing we selected two correctly regulated lines (A127 and M268) and two lines that are susceptible to induction of silencing (J253 and D184) for further study.
In order to further explore the basis for this chromatin-mediated gene silencing, we performed ChIP assays to measure levels of acetylation and tri-methylation of histone H3 K9 within the enhancer, promoter and coding region of the transgenes.
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It will be interesting to further explore the molecular basis of agonist-selective internalization at MC4R and to identify potential differences in phosphorylation by GRKs or arrestin binding that underlie this observation.
Here we set out to further explore the molecular basis of this force-balance, asking whether myosin II contributes to the early spindle assembly, perhaps by generating a cortical flow that pulls actin radially outward, and with it the cross-linked astral MTs [2].
To further explore the molecular basis of the role of Prdm14, we turned to the more tractable ES cells where Prdm14 plays a role in promoting pluripotency [ 6 9].
To further explore the mechanistic basis of Flt3-ITD-induced myeloid bias of early lymphoid progenitors, we examined Pu1 protein expression using a Pu1-YFP reporter line.
To further explore the molecular basis for the neutralizing capacity of these THc-expressing replicon immunizations, a solid-phase assay was performed, which allowed the assessment of the ability of sera antibodies to inhibit the binding of THc to GT1b.
To further explore the genetic basis of ecotypic differentiation, a genome scan was performed using 14,708 DArTseq markers to identify "outlier markers" undergoing differential selection between the precocious Lighthouse population (n = 32) and the nearest normal population, Tidal River (n = 30).
To further explore the mechanistic basis for this, we first investigated two parameters that could contribute to TKI resistance: (1) EGFR levels and (2) BCRP SNPs that may have a function in the observed TKI-resistant phenotypes.
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