Importantly, adding the mark-recapture abundance estimates to the objective function substantially improved the performance of the H a, s, yr) sub-model in the Stochastic Rates scenario (Figure 3) and also resulted in less biased estimates of mean abundance for both sets of model estimators in all scenarios (Table S1).
The systemic nature of RA causes, next to loss of joint function, substantially decreased quality of life and increased mortality of patients.
In line with previous studies, ET-1 significantly induced melanogenesis followed by increases in melanosome transport in melanocytes and in its transfer to keratinocytes while inhibition of ET-B function substantially depressed melanogenic ability in tissue-cultured SLs.
How this affects the function of PAB6 is presently unknown, but the ability to bind poly(A) RNA while unable to interact with PAM2 motif-containing proteins may alter normal PABP function substantially.
LRP-deficient cells secrete less Aβ and restoring LRP function substantially increases Aβ production [15].
Here, 'fragile' should not necessarily be equalized with 'essential' but the organism may be viable, however, it's overall function substantially impaired.
Approach C is recommended for conserved populations because for all three breeds the use of this objective function substantially decreased the migrant contributions, increased the NGE, and caused only a moderate decrease of gene diversity.
In fact, over the years the amount of drugs I use has substantially increased; to function normally I now need to spent £50 a day on heroin.
In vivo studies revealed that ACSVL3 loss-of-function substantially inhibited the ability of neurosphere cells to propagate orthotopic tumor xenografts.
