Sentence examples for to fully inhibit from inspiring English sources
Our observations indicated that in contrast to somatic cells with dually controlled Separase, PGCs have insufficient Securin to fully inhibit Separase and, therefore, their inhibition of Separase is dependent mainly on inhibitory phosphorylation.
These observations suggest that non-covalent inhibition of 20S β5 activity alone is not sufficient to fully inhibit the proteasomal degradation of either 4xUb-Luc or IκBα, at least over the time-scale of these cell-based assays.
Importantly, we identify potent BLMH inhibitors that are able to fully inhibit endogenous BLMH activity in intact cells.
However, early clinical data for direct FLT3 inhibitors provided only modest results because of the failure to fully inhibit FLT3.
As can be seen, although it does inhibit JNK1/2, SP600125 has relatively low potency, only fully inhibiting JNK1/2 activity above 10 μM, in agreement with previous studies that use SP600125 at 25 μM to fully inhibit JNK1/2 [17].
Therefore, it is possible that neurons do not contain enough Smac protein to fully inhibit XIAP.
However, the fact that the increase in LH does not have to be fully inhibited to have an adverse effect on ovulation does indicate that it is likely to be a sensitive step in the control of ovulation, although not necessarily a nonthresholded step.
The authors reported that B. subtilis biofilms contain 50 80 μM norspermidine and that just 25 μM exogenous norspermidine added to the growth medium prior to inoculation fully inhibits biofilm formation without inhibiting planktonic growth.
These studies implicate Drp1 as a key player in apoptosis, with Drp1 inhibition reported to slow, rather than fully inhibit apoptosis (Frank et al., 2001; Estaquier and Arnoult, 2007).
It should be fairly intuitive that y and z are competing for dominance, and if y is ever able to fully activate itself and fully inhibit z, then z is forever inhibited, and vice versa (subject to a suitable reaction kinetics).
As a consequence, hysteresis effects might shift the secondary nucleation step to late stages of aggregate growth or even fully inhibit transformation to the thermodynamically preferred structure.
