Thus, there is a real need to understand how to produce cells that are sufficiently differentiated to (a) model pathological aspects of disease; (b) faithfully predict drug safety; and (c) integrate effectively into tissue when transplanted.
Additionally, we showed that information flow scores faithfully predict transcriptional changes in response to rapamycin-treatment, which validates accuracy of predicted effectors.
However, CBF alone cannot faithfully predict tissue fate; the duration to which neurons are under compromised perfusion is equally critical for final neuronal fate as shown in Figure 2 [ 27, 30, 31].
Interestingly, a phagocytosis assay showed that the LL-37-differentiated cells retain their phagocytic function similar to the other generated macrophages except LPS-generated macrophage (Figure 4B), although this assay may not faithfully predict phagocytosis of opsonized bacteria.
And did you faithfully predict the recent Ukraine crisis?
Although high-throughput screening assays exist, they do not faithfully predict the result of the Ames test and at the same time require a significant investment [14, 15].
The results demonstrate that the developed method can faithfully predict the deformation of the structure and most importantly the delicate second sound effect of heat conduction in both one and two-dimensional solids whilst it is usually difficult to model, especially in two-dimensional, by using the transform method.
Evidence from recent studies demonstrates that histone modifications faithfully predict cell fates in various cellular contexts [ 17].
The uni-variate gene exression average classifier could also faithfully predict MYCN status in neuroblastoma and histopathological subtype in lung cancers.
Our simulation results demonstrate that the model faithfully predicts the anisotropic swelling of lithiated SiNWs observed from previous experimental studies.
