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If the rate is adjusted to exclude counting "sequenceable" CpGs in repeat-region DNA, the richness of DMCs in exons and CGIs is still apparent (11.41% and 15.9%), suggesting these regions attract more epigenetic reprogramming in neoplastic cells.
A loop-flipping event is counted if a given loop switches from a cytoplasmic to periplasmic (or vice versa) position according to the definitions in the main text and if the y-position of the reference bead in the loop (defined in the main text) is at least 4.5 σ after the flip (to exclude counting the rapid flipping of loops within the translocon channel).
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The decision to exclude counts of 'I', 'D' and 'G' events was made on the basis that these events are relatively rare in mammals and contribute little to the prediction problem while greatly increasing the number of features.
For this purpose, all questions/statements included in these instruments were listed to exclude double counting.
In order to avoid heterogeneity of the study population and disease definition as well as statistical power both authors agreed to exclude bacterial count cut off < 105 CFU/mL.
Each pup was individually marked to exclude double counts, and we continued observing the breeding burrows for several days after natal emergence to ensure that no unmarked juveniles were left.
Results were used to calculate the occurrence of neoplastic types in the two data sets and by calculation of the number per annum corrected for the share of the two laboratories of all submissions – to exclude double counts - in the entire (with or without pedigree) Dutch Golden Retriever population to assess an EIR.
4) determine gene family clusters for the proteome 5) adjust z-scores to exclude duplicate tripeptide counts arising from within individual gene families.
After 48 h, the cells were detached using trypsin, stained with trypan blue to exclude dead cells, and counted using a haematocytometer counting chamber (VWR International, Darmstadt, Germany).
The cost of these measures, most of which were announced in the November 2008 Pre-Budget Report, was about £20 billion excluding counting loan guarantees.
We traced all patients to exclude any double counting between the general hospital and the mental health unit (Hergest).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com