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to exacerbations
noun
An increase in the severity of something (such as a disease)
synonyms
Exact(60)
Some patients appear intrinsically more susceptible to exacerbations than others (18), and an important phenotype in COPD is the "frequent exacerbator" (35).
The precise direct and indirect mechanisms of viral contribution to exacerbations must still be elucidated.
Exclusion criteria include presence of a chronic inflammatory disease or treatment with steroids or any other immunomodulatory treatment that is unrelated to exacerbations of COPD.
Alternative strategies for drug development involve the identification of key factors common to exacerbations induced by a range of different viruses.
Withdrawal from the study due to exacerbations during the treatment period was significantly increased (P<0·01) in the theophylline group.
COPD patients are also prone to exacerbations associated with bacteria infection and colonization [23].
Infection with Epstein-Barr virus in adolescent CF patients has been linked to exacerbations and poor clinical outcomes, and has also been observed in adults [41].
3 A high proportion of the costs of managing COPD is attributed to exacerbations.
Persistent inflammation and oxidative stress contribute to exacerbations and disease progression.
A high proportion of patients (39%) took a 'wait and see' approach to exacerbations (Table 3).
A high proportion of patients (39%) took a 'wait and see' approach to exacerbations.
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