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Because the functional tests to establish the function of EDARADD (mentioned above) were carried out in mouse, where the isoform A is absent, or in human, selecting the human-mouse conserved B isoform, it is currently unknown whether the two isoforms have a similar or a very different function.
These results provide the directions for the design of experiments to establish the function of PE and PPE proteins.
Investigating the domain architecture of a given protein and deriving its evolutionary origins is a starting point to establish the function of a novel protein.
However, further studies are needed to establish the function of these enzymes in the lifestyle of P. acidipropionici.
Further complementation studies are essential to establish the function of various isoforms of WRI in nonseed tissues.
To establish the function of DnaA binding to sequences other than oriC, we examined transcriptional profiles in DnaA-overproducing and -depleted cells using the high-density tiling chip employed for ChAP-chip analysis.
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Notable also were his vivisection experiments, such as tying off the recurrent laryngeal nerve to show that the brain controls the voice, performing a series of transections of the spinal cord to establish the functions of the spinal nerves, and tying off the ureters to demonstrate kidney and bladder functions.
The challenge for the future is to establish the functions of all of these genes.
The publication drew immediate attention because the array promises to establish the functions of a myriad of enzymes and probe the metabolisms of bacteria and other kinds of cells.
To establish the functions of different carp chemokines during inflammation, we performed an extensive analysis of expression profiles of carp CXCL8_L2, CXCa_L1, CXCb and the receptors CXCR1 and CXCR2 after in vitro stimulation of leukocyte subpopulations.
To establish the functions of McFAD2 and McFAD2v, the open-reading frames of these enzymes were assembled under control of the GAL10 promoter in the pESC-URA vector and expressed in Saccharomyces cerevisiae.
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