Sentence examples for to ere from inspiring English sources

The SNPs at the 21q22.3 ERE were found to affect the binding of ER to ERE, leading to a difference in ER-regulated transcription, and to be significantly associated with OS and DFS.

We then demonstrated that butyrate induces binding of nuclear proteins specifically to ERE since point-mutated ERE constructs did not bind nuclear proteins following butyrate treatment.

Antiestrogenic actions mediated via AhR are well described, in which AhR:ligand inhibits ER binding to ERE (Pocar et al. 2005) and increases proteasomal degradation of ER (Wormke et al. 2003).

In the classical pathway, E2 ER binds directly to ERE DNA motifs in genes (ERE dependent), whereas ERα can interact with other DNA-binding transcription factors by protein protein interaction (ERE independent) (Hall et al. 2001).

E2 binds directly to ER thereby facilitating ER dimerization and subsequent high affinity binding to ERE (referred to as steroid-dependent ER activation) [13].

ER interacts with RelA and enhances binding of both ER and RelA to ERE, resulting in activation of prostaglandin-E synthase-1 (PGES) gene expression leading to an increase in PGE2 production [ 102].

The well-known mechanism in which ER binds to EREs to mediate the expression of ER-regulated genes [ 2- 4] prompted us to speculate whether the SNPs of EREs and ESR1 might be jointly associated with breast cancer.

In general, ERs, along with various coregulators, are recruited to EREs present in the promoters of E2-responsive genes [ 13].

Figure 6 depicts the (a) EER plots and (b) ROC plots of EP + DBR, EP + BRGC, and EP + LSSC discretization schemes with reliable feature-selection schemes (identified in part I) applied to ERE-extracted features from (I) FERET, and (II) FRGC datasets.

E2 modulates transcriptional regulation of gene expression through selective binding to EREs, and the ERα F promoter contains a half ERE consensus binding site [11], [12].

In addition, Kraus et al [26] has reported that ERRα can modulate estrogen responsiveness and effectively compete with ERα for the binding to EREs.