This leads us to propose that one essential role of the extra-embryonic lineages in peri-implantation EPI morphogenesis is to provide ECM components of the basal membrane to enable EPI maturation.
If the former have evolved from the latter, the constraints on the sequence of a GFP-like protein, which has to enable the maturation of a chromophore or a fluorophore, have apparently been lifted in the G2 domains, which became coopted into a mutidomain polypeptide that mediates protein-protein interactions in the basal membrane of metazoa.
The Post also reported that the administration was looking to request $150 million in fiscal year 2019 "to enable the development and maturation of commercial entities and capabilities which will ensure that commercial successors to the ISS — potentially including elements of the ISS — are operational when they are needed".
The data imply existence of simultaneous processes in stroma-rich tumors enabling maturation either towards a chromaffin or a ganglionic phenotype in neighbouring cells, putatively reflecting alternative embryonal programmes in autonomic nervous system development.
Our results demonstrate that exogenous expression of apoA-I promotes cardiac differentiation of pluripotent stem cells and enables maturation of calcium handling properties of pluripotent stem cell-derived cardiomyocytes.
It is apparent that intraepithelial T cells crossing the pb/im interface degenerate, and such apoptosis may be required for a release of substances enabling maturation of epithelial cells.
One of the most relevant hypotheses is that Notch may act as an on/off switch, either enabling maturation of the articular cartilage by promoting cell proliferation or acting as a terminal differentiation potential leading to bone formation (and bone elongation after birth).
During the humoral immune response, B cells undergo a dramatic change in phenotype to enable antibody affinity maturation in germinal centers (GCs).
Many of the other stored maternal mRNAs have to be strongly translationally repressed to enable the subsequent stages of growth, maturation and fertilisation of the oocyte [71].
These factors are not absolutely required for meiotic maturation or its negative regulation in the absence of sperm, but function cumulatively to enable somatic control of meiotic maturation.
After being generated from phialides through repeated asymmetric mitotic cell divisions, conidia need to undergo a maturation process to enable the long-term viability [9].
