The mechanisms of this process need to be elucidated for example by learning diaries [ 48].
Firstly, the different regulation roles of inhibitory receptors remain to be elucidated, for example, PD-1 and TIM-3 may regulate different process of T-cell exhaustion.
The molecular machinery required for the DIF-1 response in D. discoideum has yet to be fully elucidated; for example, how cells receive the DIF-1 molecule remains unclear.
Furthermore, although storage conditions evaluated here and especially refrigeration are most commonly used, it may be of importance to elucidate whether, for example, more-gentle freezing/thawing conditions may be also appropriate for the storage of BAL specimens.
Future studies are warranted in order to elucidate whether, for example, the BAT3 C allele encodes a protein with modulated chaperone activity, which may lead to increased HLA class II expression in APCs and/or to enhanced Th1 cell activation in the context of allo-HSCT rejection.
Asked to elucidate, he said: "For example, we have administered corporal punishment and the person has received ill-fate".
Further work is needed to elucidate potential biological mechanisms; for example, the role of chronic inflammation (Smedby et al, 2008; Chang et al, 2010).
Additional studies are needed to verify this observation and to elucidate the underlying mechanisms, for example, the generation of plasma cells with their various effector functions and other factors.
However, the mapping of RNU43 to RPL3-linked Affymetrix probe sets has not shown a good link between RPL3 and RNU43, so further work is required to elucidate the reason for the difference (for example trough differential regulation of a snoRNA to its host gene, or through alternative splicing, as there are several transcript variants giving rise to different isoforms of RPL3).
MR was implemented, for example, to elucidate the detrimental role of intrauterine alcohol exposure on cognitive performance later in life [ 81].
