Finally, Cyclin D1 is necessary to effect transformation of cells downstream of specific oncogenic stimuli [30].
A pop composer of extended forms needs to know not just the vast range of musical idioms now suitable for transformation, but also the harmonic and theoretical underpinnings needed to effect such transformations.
And like Ms. Chekerdjian, the outfit also employs classically trained local artisans to effect the transformations.
Was a foreign invasion needed to effect the transformations brought about by the French revolution?
Taken collectively, however, energy scenarios can help bring into sharp focus a range of plausible futures — information decision-makers can use to assess the scale and cost of the technological changes needed to effect significant transformations in energy production and consumption.
In a speech on December 10 , 1984 he spoke of the need to effect "deep transformations in the economy and the whole system of social relations," to carry through the policies of perestroika ("restructuring" of economic management), the "democratization of social and economic life," and glasnost.
Representative case studies are presented next to illustrate how chemically induced cytoskeletal changes, biomechanical responses and signals from the intracellular regions act in concert with the chemomechanical environment of the extracellular matrix and the molecular tumorigenic signaling pathways to effect malignant transformations.
Rather, as was true for many of their foresisters, they had important matters of concern about which they thought seriously, discussed in their women's clubs and other organizations, wrote and spoke, and worked with determination to effect progressive transformations in the lives of women and their families as well as for the racial group and the society as a whole.
Finally, the offloading and cyclization of the initially formed linear apratoxin A scaffold represents a fundamentally new mechanism by which to effect these transformations.
Sweating by now, and covered with dust, she got to work to effect this transformation.
