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To determine whether perturbation of any given gene in a genome suffices to drive subsequent genetic changes, we analyzed the yeast knockout collection for secondary mutations of functional consequence.
With an estimated maximum voltage gain of 2.6, the technology is sufficient to drive subsequent components in logic circuits.
The segregation of cells into two non-intermingling populations is thought to drive subsequent specializations, including increased apical cell area, actomyosin enrichment and the expression of local organizer signals (reviewed by Dahmann et al., 2011; Batlle and Wilkinson, 2012).
It is thus possible to identify "interesting" sequences such as putative genes or regulatory regions, and use these data to drive subsequent experimental analysis or to strengthen the reliability of independent computational data (i.e. de novo gene finding data).
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This inspiration can drive subsequent benefits to the rest of us, including recreational athletes and weekend warriors alike.
This system was used to reprogram the cell lineage of stem cells and drive subsequent phenotypes [ 90].
The suggestions that T. cruzi infection contributes to accumulation of LkDTs, and that genotypic and phenotypic alterations would drive subsequent autoimmune destruction of "self" target tissues [3], [20] provided the stimuli for our efforts.
This is not a proof of concept — you should do these earlier as a way of identifying opportunities — but a banner project that can drive subsequent investments.
Finally, we were able to confirm that positively charged organic interfaces can act as templates for biomineral growth because counterion-mediated Ca2 + accumulation on these surfaces can drive subsequent crystal growth.
Since the dissolution of arsenopyrite is oxidative in nature, oxidized species on the surface could drive subsequent dissolution of arsenopyrite.
After CKD has developed, other more dominant pathologies (such as hyperfiltration and fibrosis) may drive subsequent eGFR decline.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com