Exact(2)
Preclinical data has illustrated that UA emerges as a promising anticancer agent, and it would be meaningful and challenging to develop this compound to be a novel antitumor drug.
Preclinical data has illustrated that BITC emerges as a promising anticancer agent and it would be meaningful and challenging to develop this compound to be a novel antitumor drug.
Similar(58)
To further develop this compound we modified its structure to obtain more potent inhibitors of the PI3K/Akt pathway.
Further investigations on identifying the molecular target(s), interaction with which 1, 9 PA promotes HIF-1α ubiquitination, are needed to develop this lead compound into a new class of anticancer agents.
This study could provide a better understanding of how BITC exerts its antileukemic activity in vivo and aid in developing this compound to treat leukemia and possibly other hematologic malignancies.
Keys to developing this approach for new target compounds are: (i) sufficient reliable NMR data for the target analytes; (ii) comprehensive literature mining; (iii) establishment and maintenance of spectral databases; and (iv) validation of the spectral predictions.
The aim of this work is to develop a compound transdermal patch containing teriflunomide (TEF) and lornoxicam (LOX) to transport these drugs across the skin with the isochronous permeation rates for RA therapy and investigate intra-articular delivery of TEF and LOX following transdermal patches applied topically.
In the drug industry, he added, "where you need 8to1010 years to develop a new compound, this long-term perspective is vital".
Therefore, there is an urgent need to search for alternative antimicrobial target to develop antimicrobial compound against pneumococcal biofilms.
We took advantage of this feature to develop amphiphilic compounds able to build a network of salt bridges with these basic residues, in close proximity to the membrane region where such molecules accumulate upon membrane protein extraction.
This study tried to develop novel compounds with much greater anti-HCMV activity than GCV.
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