Given the poor outcomes associated with resurgent AR activity and CRPC development, it is imperative to develop new means for enhancing therapeutic efficacy and thus to prevent the transition to CRPC.
This summer, John R. Bolton, under secretary of state for arms control and international security, testified in Congress that the goal was to develop "new means to disrupt the proliferation trade at sea, in the air, and on land".
The program, which unites 26 comprehensive cancer centers in the United States along with more than 100 scientists worldwide, is planning to enroll more than 10,000 asymptomatic women to develop new means for accurately detecting early-stage cancer.
As they evolved from lunged fish, amphibians had to make certain adaptations for living on land including the need to develop new means of locomotion.
This observation emphasises the need to develop new means of increasing the participation rate and obtain novel screening methods with higher sensitivity than Pap-smear cytology (Sanner et al, 2009; Gok et al, 2010).
Given the expanding indications for use and the complexity of these devices, there is an urgent need to develop new means of ICD follow-up, so as to optimize patient safety and the use of healthcare resources.
