Given the rapid spread of diagnostic sequencing and direct-to-consumer testing, it may be appropriate to begin to identify an intermediate category of "actionable" variants, for which evidence is insufficient to establish unequivocal clinical utility but is sufficient to determine how already available information could be used.
Through the increase in genomic data, Verge can use its network algorithms to determine which already-FDA-approved drugs (with expired patents) affect various genes in the body.
The mechanism 'We already have ways to address this problem' points to the need to determine whether communities already have strategies in place to address sexual violence which may be preferred or that can be incorporated into introduced interventions, prior to their commencement.
"He was quite determined already then.
This issue will have been determined already and is a question of law not fact.
Investigators are still trying to determine whether others already in custody also have ties to Al Qaeda, the officials said.
Metadata enables the analyst to determine what has already been built.
We wanted first to determine whether they already use any of the agile techniques, and further on - using regression analysis - we determined the actual contribution of individual agile techniques to the project's success.
When the PR person doesn't hear back, instead of sending out one of those "just circling back" emails to determine interest, they already know I read the email and followed through by viewing the URL it included.
It shouldn't take two years to determine what we already know: mountaintop removal is one the most environmental destructive activities, especially for our waterways.
Upon completion of the 1000 Genomes project (http://www.1000genomes.org), incorporation of this information can also be utilized to determine variants not already identified in public databases.
