Sentence examples for to demonstrate response from inspiring English sources

We postulated that inability to demonstrate response in non-BRCA carriers in which BRCA is inactivated by other mechanisms or with deficiency in homologous recombination for DNA repair is due to lack of molecular markers that define a responding subpopulation.

The study utilized an optimal two-stage design (Simon, 1989); the first 19 evaluable patients had to demonstrate response to treatment in at least five patients before the second stage could proceed to enter the remaining patients.

However, only continuously applied low dose oral etoposide, paclitaxel, gemcitabine, and, most recently, oxaliplatin have thus far been able to demonstrate response rates of about 13 20% in patients with cisplatin-refractory germ cell cancer (Miller and Einhorn, 1990; Motzer et al, 1994; Bokemeyer et al, 1996, 1999; Einhorn et al, 1999; Kollmannsberger et al, 2001).

As the paradigm of patient selection for AD-modifying candidate therapies shifts to an enrichment of the MCI population, drug developers work to reduce costs of clinical trials by aiming to demonstrate response over a shorter duration and with fewer numbers of subjects.

Although pancreatic fat content was 30% higher in the diabetic group, the study was powered to demonstrate responses to the dietary intervention rather than to test differences from weight-matched non-diabetic individuals.

Illustrative quotes from adolescents selected to demonstrate responses which were common, contrasting or representing a summary of a topic, are provided in below with assignment of IDs and adolescent sex and year level.

TMZ was administered to patients who demonstrated response to it during the treatment at diagnoses.

The results of this study show the thermal response method is suitable to demonstrate the response of parchment to RH change; however, it did not provide any specific guidance for setting environmental parameters for parchment.

Most early phase programs use markers of pharmacodynamic response and target engagement/specificity to demonstrate pharmacologic response, including CSF, plasma, and imaging-based biomarkers.

Banks, pension funds, universities, religious groups, cities and councils are under intense pressure to demonstrate a response to risks posed by climate change.

Numerical results are presented to demonstrate the response in terms of the transverse deformation and stresses in the composite sandwich plate.