Sentence examples for to delineate the function of from inspiring English sources

As such, it may be of benefit to delineate the function of some of these factors in the tumor immune microenvironment in future studies.

To delineate the function of mir-148 and let-7b during lens regeneration we performed gain- and loss-of-function experiments.

Furthermore, the non-canonical Wnt/PCP pathway is not yet active at this stage and so we took advantage of these canonical Wnt/β-catenin-responsive cells to delineate the function of Nkd1 in antagonizing canonical Wnt/β-catenin signaling, hereafter referred to as Wnt signaling.

In our efforts to delineate the function of Rest during neural development, we generated several Rest deficient ES cell mutants to elucidate the role of Rest in the transition from pluripotent ES cells to multipotent NSCs and subsequently to mature neurons.

21, 22 The accumulating evidence on innate receptors has enabled us to delineate the function of BCG reagents.

However, there is still insufficient annotation of this region and little further investigation has been undertaken to delineate the function of this domain.

Site-directed mutagenesis and a comparative characterisation of the kinetic parameters, pH dependency of activity and thermal stability of mutant and wild-type enzymes have been used in association with crystallographic analysis to delineate the functions of several active site residues in a novel glycoside hydrolase family 8 xylanase.

Further detailed investigations will be needed to delineate the functions of tsRNAs in leishmania biology, what roles they play in parasite-parasite, parasite-vector or parasite-host interactions, whether this involves their association with the host RNAi machinery and how they are targeted for exosomal packaging.

Therefore, futher studies are needed to delineate the role of platelet function testing across the spectrum of symptomatic coronary artery disease.

Thus the development of new isoenzyme-selective probes would be able to better delineate the function of a single isoenzyme and its individual contribution to the metabolism of a particular substrate.

Our major aim was to delineate the role of ABCB6's unique N-terminal domain in regulating ABCB6 function and intracellular targeting.