Exact(8)
Interestingly, α4-1BB appeared to decrease the proliferation of tumor-infiltrating Tregs, but much of this effect was lost in combination with CTLA-4 blockade (Figure S6).
However, aspirin failed to decrease the proliferation of the alveolar epithelium.
Kefir was found to decrease the proliferation of both cell lines in a dose- and time-dependent manner.
BPA (50 μM) was also found to decrease the proliferation of cultured human endometrial endothelial cells (Bredhult et al. 2009).
In the present study we analyzed whether a long-term activation of ERbeta by selective agonists was able to decrease the proliferation of Rv1 PC cells and, if so, which are the underlying molecular mechanisms.
The complex regulation of endocrine progenitor cell proliferation is not surprising given that overexpression of Insm1 in the developing neural cortex has been shown to decrease the proliferation of less differentiated apical progenitor cells but to increase the proliferation of more differentiated intermediate basal progenitor cells (Farkas et al., 2008).
Similar(52)
Moreover, the expression of miR-126* was sufficient to decrease the proliferation rate of t(4; 14) MM cells.
Thus, up-regulation of these 'tumor suppressor genes' is likely to decrease the proliferation rate of human bmMSC.
Like Treg cells, MSCs migrate to the joints where they can act locally inside the inflamed synovium to decrease the proliferation and function of immune cells via the secretion of inhibitory soluble factors.
However, miR-146a clearly impairs cell proliferation (miR-146a) and exerts a synergistic effect in combination with VitD3 (miR-146a + VitD3) to decrease the proliferation rate growth of U937-miR146a cells, as compared with control cells.
Bisphosphonates have been shown to decrease the proliferation and viability of human tumor cells lines, as well as to increase the apoptotic index of the human tumor cell lines [ 13, 16].
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