Furthermore, TSA and vorinostat treatment was shown to decrease the expression of EZH2 in cell lines that re-expressed SOX11, but not in others, further supporting an important role of EZH2 and H3K27me3 methylation in the maintenance of SOX11 silencing.
Varied scaffold chemistries suggest the ability to decrease the expression of M1 macrophages.
Baicalin possesses the ability to decrease the expression of pro-inflammatory cytokines and nuclear factor (NF -κB activity.
On the other hand, the presence of inorganic sulfate is known to decrease the expression of several bacterial sulfatases (Kertesz 2000).
We designed small interfering (siRNA) sequences complementary to Syk coding regions to decrease the expression of Syk in the human macrophage cell line, THP-1.
Previously, it was reported that HBx was able to decrease the expression of PTEN [25].
We used RNAi to decrease the expression of p300 to further investigate its role in DEX-induced histone hyperacetylation.
Interestingly, Wnt3a treatment alone was actually found to decrease the expression of smooth muscle α-actin in their study.
It is suggested that AvrA expression in the WT Salmonella is able to decrease the expression of inflammatory cytokine IL-6.
For example, cAMP in vascular SMCs was shown to decrease the expression of cyclin D1 and cdk2 as well as the activation of extracellular signal-regulated kinase (ERK).
For example, FK-228, a depsipeptide HDAC inhibitor, is reported to decrease the expression of EGFR in lung cancer cells [30].
